Genes and homology
نویسندگان
چکیده
منابع مشابه
Genes and homology
What is your favourite/least favourite conference? I don't have a favourite conference series, and I can only guess what my least favourite would be. The most exciting single conference that I ever attended took place in Soviet Armenia in 1971. It was entitled “Communication with Extraterrestrial Intelligence”. What made it memorable was the mix of bright and lively participants who covered eve...
متن کاملHomology search for genes
MOTIVATION Life science researchers often require an exhaustive list of protein coding genes similar to a given query gene. To find such genes, homology search tools, such as BLAST or PatternHunter, return a set of high-scoring pairs (HSPs). These HSPs then need to be correlated with existing sequence annotations, or assembled manually into putative gene structures. This process is error-prone ...
متن کاملHomology Search for Genes Using Biased HMMs
Motivation: Life science researchers often require an exhaustive list of protein coding genes similar to a given query gene. To find such genes, homology search tools, such as BLAST or PatternHunter, return a set of high-scoring pairs (HSPs). These HSPs then need to be correlated with existing sequence annotations, or assembled manually into putative gene structures. This process is error-prone...
متن کاملNew human and mouse microRNA genes found by homology search.
Conservation of microRNAs (miRNAs) among species suggests that they bear conserved biological functions. However, sequencing of new miRNAs has not always been accompanied by a search for orthologues in other species. I report herein the results of a systematic search for interspecies orthologues of miRNA precursors, leading to the identification of 35 human and 45 mouse new putative miRNA genes...
متن کاملIdentifying cycling genes by combining sequence homology and expression data
MOTIVATION The expression of genes during the cell division process has now been studied in many different species. An important goal of these studies is to identify the set of cycling genes. To date, this was done independently for each of the species studied. Due to noise and other data analysis problems, accurately deriving a set of cycling genes from expression data is a hard problem. This ...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2004
ISSN: 0960-9822
DOI: 10.1016/j.cub.2004.04.016